The Shift from Batch to Continuous-Flow Reactors

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Up-flow 5403 Tubular Reactor System with 300 mL heated volume, one purge line, one gas feed, two liquid feeds, product cooling condenser, and automated 2-phase back pressure regulator. An automated liquid sampler captures representative samples at a user-programmable interval.
5403 Tubular Reactor System with automated liquid sampler.

Recently, continuous-flow reactors have become commonplace in pharmaceutical laboratories and production facilities. This style of reactor permits easier automation of sequential and parametric changes in temperature, pressure, flow rate, and residence time. The amount of product becomes a function of time, not larger equipment, thereby leading to increased safety as smaller amounts of materials are present at any given time.

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